Mechanisms of Cellular Organization
Fall 2007
Room 2-501 BSB
MWF 2:30 - 3:30

FACULTY

 

Rob Piper            Physiology                    6-452 BSB           335-7842   robert-piper@uiowa.edu

  (Co-Director)

Mark Stamnes    Physiology                    5-550 BSB           335-7858   mark-stamnes@uiowa.edu

  (Co-Director)

Charles Yeaman Anatomy &Cell Biol.      1-632 BSB           335-8782   charles-yeaman@uiowa.edu

 

Lee-Ann Allen      Internal Medicine          D154 MTF           335-4258   lee-ann-allen@uiowa.edu

 

COURSE SCHEDULE

AUGUST

 

 

 

 

 

27

Monday

Organization of course. Introduction to Membranes

Piper

SPECIFIC AIMS ASSIGNED

 

29

Wednesday

How proteins cross membranes; 

Piper

 

 

31

Friday

How proteins cross membranes - continued

Piper

Homework #1 asigned

 

SEPTEMBER

 

 

 

 

 

3

Monday

LABOR DAY

 

 

 

5

Wednesday

Functions  of the endoplasmic reticulum and Golgi

Piper

 

 

7

Friday

Discussion of Homework

Piper

Homework #1 Due

no points

 

 

 

 

 

 

10

Monday

Cellular  response to damaged proteins

Piper

 

 

12

Wednesday

Vesicle formation at the ER

Piper

homework #2 assigned

 

14

Friday

Vesicle formation at the Golgi and TGN

Piper

 

 

 

 

 

 

 

 

17

Monday

Discussion of Homework

Piper

Homework #2 Due

25

19

Wednesday

Membrane fusion - SNARE and Rab function

Sheff

Homework #3 assigned

 

21

Friday

constitutive and regulated Exocytosis

Sheff

 

 

 

 

 

 

 

 

24

Monday

Discussion of Homework

Sheff

homework #3 due

25

26

Wednesday

Clathrin  mediated internalization

Sheff

 

 

28

Friday

The  endosomal system

Sheff

EXAM A POSTED

 

OCTOBER

 

 

 

 

 

1

Monday

Discussion or Lecture

Sheff

 

 

3

Wednesday

Lysosomes

Sheff

 

 

5

Friday

 Actin and actin binding proteins

STAMNES

EXAM A DUE

75

 

 

 

 

 

 

8

Monday

Cell  motility and Rho GTPases

STAMNES

homework #4 assigned

 

10

Wednesday

Actin-based motility continued

STAMNES

 

 

12

Friday

Discussion of Homework

STAMNES

Homework #4 Due

no points

 

 

 

 

 

 

15

Monday

Microtubules

STAMNES

Homework #5 Assigned

 

17

Wednesday

MAPs  and intermediate filaments

STAMNES

 

 

19

Friday

Discussion of Homework

STAMNES

Homework #5 Due

25

 

 

 

 

 

 

22

Monday

Molecular motors

STAMNES

 

 

24

Wednesday

EXAM (B)-In class

STAMNES

EXAM B

50

26

Friday

Cilia and Flagella I

YEAMAN

 

 

 

 

 

 

 

 

29

Monday

Cilia and Flagella II

YEAMAN

Homework #6 Assigned

 

31

Wednesday

Nuclear-cytoplasmic transport

YEAMAN

 

 

 

 

 

 

 

 

NOVEMBER

 

 

 

 

 

2

Friday

Discussion of Homework

YEAMAN

Homework #6 Due

25

 

 

 

 

 

 

5

Monday

Mitosis I: Changes in nuclear & cytoplasmic organization (Prophase through metaphase

YEAMAN